The Hush Post: A Boeing 737 plane has crashed shortly after taking off from airport in Havana, Cuban, as per a state-run website Cubadebate.
As many as 104 people travelling onboard are feared killed.
The plane came down minutes after take-off and exploded at Jose Marti International Airport in Havana.
Firefighters ran to the scene and are trying to get the fire under control. A heavy police presence is also at the airport following the crash.
Others said the plane burst into a fireball as it crashed between the airport in southern Havana and the town of Santiago de las Vegas.
The plane reportedly belongs to Cubana de Aviación and the ill-fated flight was on its way to Guyana.